8
ESSM
Today
Interview with Ates Kadioglu
Although non-ischemic priapism is not accepted
as emergency and usually treated with radiologi-
cal intervention, the long term erectile function
deteriorating effects of oxidative stress caused by
non-ischemic priapism should not be overlooked
and investigated thoroughly. The time limit of ED
development is still under investigation through
animal studies and human case observations.
Finally there is still no established mainstream
treatment for stuttering priapism despite the nu-
merous options such as PDE 5 inhibitors, CAMP
inhibitors. In addition there is insufficient data
in the literature to identify and treat high flow
stuttering priapism.
JIMS: Dr. Kadioglu, also you are involved
in the research of new PDE5I as Udenafil/
Avanafil, what do you think would be the
major contribution to the field?
Avanafil stands out with its fast onset time and
highly selective PDE 5 inhibition. This oral drug
keeps its efficiency even in patients who took the
pill 15 minutes prior to the intercourse. The short
onset time of the drug fills the niche of patients
who cannot plan sexual activity ahead of time.
It also has lower PDE 1 and 6 inhibition in com-
parison to sildenafil and as a result does not af-
fect retinal functions and decreases hypotension
side effect. Udenafil targets another spectrum
of patients with its relatively rapid onset time
(1.3 hours) and longer half life (13 hours). The
drug might be administered daily or demand
depending on the patient choice. While longer
half time of udenafil is a significant advantage of
the drug in comparison with sildenafil, udenafil
has fewer adverse effects than tadalafil.
JIMS: And last but not least, which do you
consider the most important challenges for
our specialty (Sexual Medicine) and for our
society (ESSM) in the next 5 years?
The innovative and fast pacing nature of tech-
nology makes the sexual surgeons’ work chal-
lenging. The ever developing pharmaceutical
therapeutics rapidly challenge surgical treat-
ments in every aspect of sexual medicine. Our
objective should be keeping up with this prompt
pace of medical technology, present our patients
with updated solutions to their problems and
integrate developments to our daily practice.
The promising new techniques such as stem cell
treatment should be administered by the urolo-
gists in the future. Peyronie’s disease surgery
will continue to be a part of our lives. I think
that the pathophysiology of the priapism will be
explained in 10 years. We will continue to implant
penile prosthesis for post radical prostatectomy
patients. For the society, the government sys-
tem should be democracy under meritocracy. All
people with merit should be represented in the
government without regard to their geographical
origin. Although I believe that the society should
take necessary action in order to protect itself,
oligarchic club nature of the society should be
changed. Because of the decline in industrial
financial support, organization of ESSM meetings
should be in attachment to national congresses.
In addition the meetings length should be de-
creased in order to cut back expenses.
It was a great pleasure to interview you;
I am convinced that your points of view,
fruits of a lifetime devoted to your work,
will be highly appreciated by our readers.
Thanks once again.
l
16
th
CONGRESS OF THE EUROPEAN
SOCIETY FOR SEXUAL MEDICINE
joint by the 12
th
Congress of the
European Federation of Sexology
29 January – 1 February 2014 l Istanbul, Turkey
