ECP 2018 Final Programme

8 ECP 2018 · Bilbao e Anna Mae Diehl (USA) Dr. Diehl is a Phi Beta Kappa, cum laude graduate of George- town University (1974), was elected to Alpha Omega Alpha as a junior medical student, and awarded the Janet M. Glasgow Award for women who graduate first in their medical school class, as well as the Kober medal for overall academic excel- lence, when she graduated summa cum laude from George- town University School of Medicine (1978). Dr. Diehl com- pleted her internship and residency in internal medicine (1978–81), as well as her fellowship in gastroenterology at Johns Hopkins University (1981-84). Dr. Diehl remains active in basic and clinical liver research, and, has a busy clinical Hepatology practice caring for patients with nonalcoholic fatty liver disease (NAFLD). Her work has led to her recognition as a thought leader in the NAFLD field. A number of universities and professional societies have honored Dr. Diehl for her contributions to the field of Hepatology and regularly invite her to present at research symposia. Dr. Diehl is viewed internationally as an authority in the liver regeneration field and is regularly invited to present state-of-the-art lectures at major scientific meetings, to author position papers for leading biomedical research journals, and to serve on scientific review panels and advisory boards that conduct research and develop clinical prac- tice guidelines for liver diseases. Dr. Diehl has been voted one of the Top Doctors in the USA and selected for Who's Who in Medicine. In the spring of 2011, the National Institutes of Al- cohol Abuse and Alcoholism conferred upon her the Jack Mendelson Award, its highest honor for research that has advanced knowledge about alcohol-related diseases, and, the Board of Trustees of the Johns Hopkins University inducted her into their elite Society of Scholars. In the fall of 2012, she was presented with the AASLD Distinguished Scientific Achievement Award in honor of her sustained scientific contributions to the field of liver disease and the scientific foundations of Hepatology. In addition, Dr. Diehl is a charter member of the NASH CRN Steer- ing Committee, an invited member of the writing group for the recently published AASLD/ AGA/ACG NASH Clinical Guidelines, and the senior author on the first chapter on NAFLD that will appear in the latest edition of Harrison's Textbook of Medicine. She won the Duke Distinguished Faculty Award in 2017 and will receive the Elizabeth Hurlock Beckman Award in fall 2018. Dr. Diehl's laboratory has received uninterrupted NIH support to investigate basic mechanisms of liver regeneration for over 20 years. Dr. Diehl has devoted her research career to unraveling the mechanisms that control liver regeneration/repair because her job as practicing clinical hepatologist is to improve the out- come of liver injury. As a hepatologist, she cares for many patients with nonalcoholic fatty liver disease (NAFLD). Dr. Diehl’s goal is to lessen the patient’s suffering and to prevent prema- ture death from liver disease. Because work in her lab suggests that bad outcomes of NAFLD (i.e., cirrhosis and cancer) result when dead hepatocytes are not regenerated efficiently, Dr. Diehl has devoted her career to: i) identifying mechanisms that promote effective liver regeneration, ii) determining which of these processes become deregulated when liver repair is defective, and iii) testing whether or not “fixing”the deregulated process will restore regeneration and improve recovery, thereby reducing liver-related morbidity and mortality. Dr. Diehl's research program on obesity-related liver disease has been supported by the NIH for more than a decade. Our findings have advanced understanding about basic mechanisms that drive NAFLD progression and provided the conceptual basis for subsequent clinical trials. The work has also led to Dr. Diehl being recognized as a thought leader in the NAFLD field. For example, Dr. Diehl is regularly invited to present her basic research at research symposia, such as FASEB Conferences and Keystone Symposia. Keynote Speakers